Detalhe da pesquisa
1.
Identification of recurrent genomic alterations in the apoptotic machinery in chronic lymphocytic leukemia patients treated with venetoclax monotherapy.
Am J Hematol
; 97(2): E47-E51, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34779028
2.
Baseline Expression of Immune Gene Modules in Blood is Associated With Primary Response to Anti-TNF Therapy in Crohn's Disease Patients.
J Crohns Colitis
; 18(3): 431-445, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37776235
3.
Diversity of CFTR variants across ancestries characterized using 454,727 UK biobank whole exome sequences.
Genome Med
; 16(1): 43, 2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38515211
4.
Functional characterization of a single nucleotide polymorphism associated with Alzheimer's disease in a hiPSC-based neuron model.
PLoS One
; 18(9): e0291029, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37751459
5.
Whole blood DNA methylation changes are associated with anti-TNF drug concentration in patients with Crohn's disease.
J Crohns Colitis
; 2023 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37551994
6.
Novel CYP1B1-RMDN2 Alzheimer's disease locus identified by genome-wide association analysis of cerebral tau deposition on PET.
medRxiv
; 2023 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36993271
7.
Cerebrospinal fluid cytokine dynamics differ between Alzheimer disease patients and elderly controls.
Alzheimer Dis Assoc Disord
; 26(4): 322-8, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22089638
8.
Effect of human cerebrospinal fluid sampling frequency on amyloid-ß levels.
Alzheimers Dement
; 8(4): 295-303, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22047633
9.
Integrative analysis of DNA methylation and gene expression identifies genes associated with biological aging in Alzheimer's disease.
Alzheimers Dement (Amst)
; 14(1): e12354, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36187194
10.
Association of peripheral blood DNA methylation level with Alzheimer's disease progression.
Clin Epigenetics
; 13(1): 191, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34654479
11.
Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank.
Nat Genet
; 53(7): 942-948, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34183854
12.
G1P3, an IFN-induced survival factor, antagonizes TRAIL-induced apoptosis in human myeloma cells.
J Clin Invest
; 117(10): 3107-17, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17823654
13.
Identification of proteasome gene regulation in a rat model for HIV protease inhibitor-induced hyperlipidemia.
Arch Toxicol
; 84(4): 263-70, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20213465
14.
Comparison of TNFα to lipopolysaccharide as an inflammagen to characterize the idiosyncratic hepatotoxicity potential of drugs: Trovafloxacin as an example.
Int J Mol Sci
; 11(11): 4697-714, 2010 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21151465
15.
A Genetic Variant in the BCL2 Gene Associates with Adalimumab Response in Hidradenitis Suppurativa Clinical Trials and Regulates Expression of BCL2.
J Invest Dermatol
; 140(3): 574-582.e2, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31465739
16.
Harnessing peripheral DNA methylation differences in the Alzheimer's Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease.
Clin Epigenetics
; 12(1): 84, 2020 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32539856
17.
Use of toxicogenomics to understand mechanisms of drug-induced hepatotoxicity during drug discovery and development.
Toxicol Lett
; 186(1): 22-31, 2009 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-18996174
18.
Role of GSK-3beta activation and alpha7 nAChRs in Abeta(1-42)-induced tau phosphorylation in PC12 cells.
J Neurochem
; 106(3): 1371-7, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18485099
19.
Gene expression profiles in livers from diclofenac-treated rats reveal intestinal bacteria-dependent and -independent pathways associated with liver injury.
J Pharmacol Exp Ther
; 327(3): 634-44, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18801949
20.
Gene expression analysis in rats treated with experimental acetyl-coenzyme A carboxylase inhibitors suggests interactions with the peroxisome proliferator-activated receptor alpha pathway.
J Pharmacol Exp Ther
; 324(2): 507-16, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18025247